Pulmonary adenocarcinoma with signet ring features: Detailed cytomorphologic analysis

Background Signet ring cell feature in lung adenocarcinoma is no longer considered a distinct subtype, but as a cytologic change that may occur in association with multiple histological patterns. Cases with signet ring cells show a strong association with Anaplastic Lymphoma Kinase (ALK) gene fusion...

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Veröffentlicht in:	Diagnostic cytopathology 2016-07, Vol.44 (7), p.607-611
Hauptverfasser:	Vallonthaiel, Archana George, Jain, Deepali, Madan, Karan, Arava, Sudheer
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adult Aged Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carcinoma, Signet Ring Cell - metabolism Carcinoma, Signet Ring Cell - pathology cytology Diagnosis, Differential DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Female Humans Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Middle Aged pulmonary adenocarcinoma Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism signet ring cells Transcription Factors
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