Multidrug resistance and tumor-initiating capacity of oral cancer stem cells

Recent studies in several tumors showed that presence of cancer stem like side population (SP) cells are responsible for chemotherapeutic drugs resistance and tumor relapse. In our present study, we have analyzed the role of SP cells in oral squamous cell carcinoma cell (OSCC) line OSCC-77. The oral...

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Veröffentlicht in:	Journal of B.U. ON. 2016-03, Vol.21 (2), p.461-465
Hauptverfasser:	Shang, Hong-Guo, Yu, Hong-Ling, Ma, Xiao-Ni, Xu, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology ATP-Binding Cassette Transporters - antagonists & inhibitors ATP-Binding Cassette Transporters - metabolism Cell Line, Tumor Cell Self Renewal - drug effects Cell Survival - drug effects Drug Resistance, Multiple Drug Resistance, Neoplasm Humans Mouth Neoplasms - drug therapy Mouth Neoplasms - metabolism Mouth Neoplasms - pathology Neoplastic Stem Cells - drug effects Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - pathology Side-Population Cells - drug effects Side-Population Cells - metabolism Side-Population Cells - pathology Verapamil - pharmacology
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