Insulin-like growth factor-1 prevents age-related decrease in specific force and intracellular Ca super(2+) in single intact muscle fibres from transgenic mice

In the present work we test the hypothesis that sustained transgenic overexpression of insulin-like growth factor-1 (IGF-1) in skeletal muscle prevents age-related decreases in myoplasmic Ca super(2+) concentration and consequently in specific force in single intact fibres from the flexor digitorum...

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Veröffentlicht in:The Journal of physiology 2003-11, Vol.552 (3), p.833-844
Hauptverfasser: Gonzalez, E, Messi, M L, Zheng, Z, Delbono, O
Format: Artikel
Sprache:eng
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