Assessing the utility of whole genome amplified DNA as a template for DMET Plus array

Large amounts of high quality DNA are typically required for high-throughput genotyping arrays but sometimes study participant DNA is in limited supply. Multiple displacement amplification (MDA)-based whole genome amplification is an in vitro technique that permits the genetic analysis of limited am...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2012-08, Vol.50 (8), p.1329-1334
Hauptverfasser:	He, Yi Jing, Misher, Anne D., Irvin, William, Motsinger-Reif, Alison, McLeod, Howard L., Hoskins, Janelle M.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADME array Biological and medical sciences Breast Neoplasms - genetics CYP2D6 DMET Plus DNA - analysis DNA - genetics Female General aspects Genome, Human Genotype Genotyping Techniques - methods Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Nucleic Acid Amplification Techniques - methods Oligonucleotide Array Sequence Analysis - methods pharmacogenetics Pharmacogenetics - methods pharmacogenomics Reproducibility of Results whole genome amplification
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