Laxitextines A and B, Cyathane Xylosides from the Tropical Fungus Laxitextum incrustatum

Bioassay-guided fractionation of the mycelial extract of a basidiomycete culture collected in Kenya led to the isolation of two new cyathane diterpenoids named laxitextines A (1) and B (2). The producer strain was characterized by detailed taxonomic studies based on rDNA using the 5.8S gene region,...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2016-04, Vol.79 (4), p.894-898
Hauptverfasser:	Mudalungu, Cynthia M, Richter, Christian, Wittstein, Kathrin, Abdalla, Muna Ali, Matasyoh, Josphat C, Stadler, Marc, Süssmuth, Roderich D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Bacillus subtilis Bacillus subtilis - drug effects Basidiomycetes Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacology Drug Screening Assays, Antitumor Female Glycosides - chemistry Glycosides - isolation & purification Glycosides - pharmacology Humans MCF-7 Cells Methicillin Resistance - drug effects Mice Molecular Structure Nuclear Magnetic Resonance, Biomolecular Staphylococcus aureus Staphylococcus aureus - drug effects
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