Manifestations of Fulminant CD8 T-cell Post-transplant Lymphoproliferative Disorder Following the Administration of Rituximab for Lymphadenopathy with a High Level of Epstein-Barr Virus (EBV) Replication after Allogeneic Hematopoietic Stem Cell Transplantation

We herein report the case of a 22-year-old woman with severe aplastic anemia who underwent allogeneic hematopoietic stem cell transplantation (HSCT). After HSCT, the Epstein-Barr virus (EBV)-DNA load in the peripheral blood gradually increased, and the patient presented with a fever and lymphadenopa...

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Veröffentlicht in:	Internal Medicine 2014, Vol.53(18), pp.2115-2119
Hauptverfasser:	Tanaka, Tomoyuki, Takizawa, Jun, Miyakoshi, Shukuko, Kozakai, Takashi, Fuse, Kyoko, Shibasaki, Yasuhiko, Moriyama, Masato, Ohshima, Koichi, Toba, Ken, Furukawa, Tatsuo, Sone, Hirohito, Masuko, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia - therapy Antibodies, Monoclonal, Murine-Derived - adverse effects Antibodies, Monoclonal, Murine-Derived - therapeutic use Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use CD8 T-cell CD8-Positive T-Lymphocytes - immunology DNA, Viral - analysis Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - virology Female Hematopoietic Stem Cell Transplantation Herpesvirus 4, Human - genetics Herpesvirus 4, Human - physiology Humans Lymphoproliferative Disorders - diagnosis Lymphoproliferative Disorders - etiology Lymphoproliferative Disorders - immunology post-transplant lymphoproliferative disorder Rituximab Virus Replication Young Adult
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