Polyethylene glycol fusion repair prevents reinnervation accuracy in rat peripheral nerve

Functional recovery following a peripheral nerve injury is made easier when regenerating axons correctly reinnervate their original targets. Polyethylene glycol (PEG) has recently been used in attempts to fuse severed peripheral axons during suture‐based repair, but an analysis of target selectivity...

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Veröffentlicht in:	Journal of neuroscience research 2016-07, Vol.94 (7), p.636-644
Hauptverfasser:	Robinson, Grant A., Madison, Roger D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axotomy Female femoral nerve Femoral Nerve - injuries Femoral Nerve - pathology motor neuron Motor Neurons - pathology Muscle, Skeletal - innervation Muscle, Skeletal - pathology Nerve Regeneration - drug effects Neural Pathways - drug effects Neural Pathways - growth & development Peripheral Nerve Injuries - pathology Peripheral Nerves - drug effects Peripheral Nerves - growth & development Polyethylene Glycols - pharmacology Rats Rats, Sprague-Dawley Recovery of Function regeneration Spinal Cord - pathology
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