Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression

Multiple myeloma (MM) pathogenesis and progression largely rely on the cells and extracellular factors in the bone marrow (BM) microenvironment. Compelling studies have identified tumour exosomes as key regulators in the maintenance and education of the BM microenvironment by targeting stromal cells...

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Veröffentlicht in:The Journal of pathology 2016-06, Vol.239 (2), p.162-173
Hauptverfasser: Wang, Jinheng, De Veirman, Kim, Faict, Sylvia, Frassanito, Maria Antonia, Ribatti, Domenico, Vacca, Angelo, Menu, Eline
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Sprache:eng
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