The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication

MicroRNAs (miRNAs) are small noncoding RNAs that are responsible for dynamic changes in gene expression, and some regulate innate antiviral responses. Retinoic acid-inducible gene I (RIG-I) is a cytosolic sensor of viral RNA; RIG-I activation induces an antiviral immune response. We found that miR-4...

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Veröffentlicht in:Science signaling 2015-12, Vol.8 (406), p.ra126-ra126
Hauptverfasser: Ingle, Harshad, Kumar, Sushil, Raut, Ashwin Ashok, Mishra, Anamika, Kulkarni, Diwakar Dattatraya, Kameyama, Takeshi, Takaoka, Akinori, Akira, Shizuo, Kumar, Himanshu
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