Female sex hormones modulate Porphyromonas gingivalis lipopolysaccharide-induced Toll-like receptor signaling in primary human monocytes

Background and Objective Female sex hormones are elevated and are potential host response modifiers during pregnancy. Modulation of immune responses by estrogen and progesterone may be responsible for periodontal inflammation. Therefore, we aimed to investigate the role of β‐estradiol and progestero...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of periodontal research 2016-06, Vol.51 (3), p.395-406
Hauptverfasser:	Jitprasertwong, P., Charadram, N., Kumphune, S., Pongcharoen, S., Sirisinha, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation - drug effects cell signaling Cyclooxygenase 2 - drug effects Cyclooxygenase 2 - metabolism cytokine Dentistry Dinoprostone - secretion Down-Regulation Estradiol - pharmacology Estrogens - pharmacology Female Gonadal Steroid Hormones - pharmacology Humans inflammation innate immunity Leukocytes, Mononuclear Lipopolysaccharide Receptors - drug effects Lipopolysaccharide Receptors - metabolism Lipopolysaccharides - pharmacology MAP Kinase Signaling System Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases - metabolism Monocytes - drug effects Monocytes - immunology NF-kappa B - antagonists & inhibitors NF-kappa B - drug effects periodontal disease Periodontal Diseases Phosphorylation Porphyromonas gingivalis Porphyromonas gingivalis - immunology Porphyromonas gingivalis - metabolism Pregnancy Progesterone - pharmacology RNA, Messenger - analysis Signal Transduction - drug effects Toll-Like Receptor 2 - antagonists & inhibitors Toll-Like Receptor 2 - drug effects Toll-Like Receptor 2 - metabolism Toll-Like Receptor 4 - antagonists & inhibitors Toll-Like Receptor 4 - drug effects Toll-Like Receptor 4 - metabolism Toll-like receptors Toll-Like Receptors - drug effects Toll-Like Receptors - immunology Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!