Study on the Association Between miRNA-202 Expression and Drug Sensitivity in Multiple Myeloma Cells

An increasing amount of experimental evidence has shown that miRNAs play a causal role in hematologic tumorigenesis. In this study, we characterized the role of miR-202 in multiple myeloma (MM) drug sensitivity. The potential binding site of miR-202 and B cell-activating factor (BAFF) was confirmed...

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Veröffentlicht in:	Pathology oncology research 2016-07, Vol.22 (3), p.531-539
Hauptverfasser:	Shen, Xianjuan, Guo, Yuehua, Qi, Jing, Shi, Wei, Wu, Xinhua, Ni, Hongbing, Ju, Shaoqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apoptosis - genetics Apoptosis Regulatory Proteins - genetics B-Cell Activating Factor - genetics Biomedical and Life Sciences Biomedicine Cancer Research Cell Line, Tumor Cell Proliferation - genetics Dexamethasone - pharmacology Drug Resistance, Neoplasm - genetics Female Gene Expression Regulation, Neoplastic - genetics Humans Immunology Male MAP Kinase Kinase 4 - genetics MicroRNAs - genetics Middle Aged Mitogen-Activated Protein Kinases - genetics Multiple Myeloma - drug therapy Multiple Myeloma - genetics Oncology Original Article Pathology Proto-Oncogene Proteins c-bcl-2 - genetics RNA, Messenger - genetics Signal Transduction Thalidomide - pharmacology
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