Applying the miniaturization technologies for biosensor design
Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars...
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Veröffentlicht in: | Biosensors & bioelectronics 2016-05, Vol.79, p.901-913 |
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description | Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars, which makes them promising candidates for mass-production. Besides electron beam lithography, stencil lithography, nano-imprint lithography or dip pen lithography, basic photolithography is the technique which is extensively used for the design of microengineered sensing systems. This technique has some advantages such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower micron-sized patterns. In this review, it has been focused on three different type of microengineered sensing devices which are developed using micro/nano-patterning techniques, microfluidic technology, and microelectromechanics system based technology.
•Micro/nano-patterning techniques provide opportunities for analysis of biological molecules.•Microfluidic technology helps to better simulate and quantificate the biologicals.•Microelectromechanical systems based sensors are promising candidates as implantable sensors. |
doi_str_mv | 10.1016/j.bios.2016.01.033 |
format | Article |
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subjects | Animals Biosensing Techniques - instrumentation Biosensing Techniques - methods Biosensors Biotechnology Design engineering Detection Electron beam lithography Equipment Design Humans Instrumentation MEMs Micro-Electrical-Mechanical Systems - instrumentation Micro-Electrical-Mechanical Systems - methods Microchip Analytical Procedures - methods Microfluidics Micropatterning Microtechnology Miniaturization Miniaturization - instrumentation Miniaturization - methods Nanopatterning Nanostructure Nanotechnology Photolithography |
title | Applying the miniaturization technologies for biosensor design |
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