Protective Effects of Kojic Acid on the Periphery Blood and Survival of Beagle Dogs after Exposure to a Lethal Dose of Gamma Radiation

In previous studies, it has been shown that pretreatment with kojic acid (KA) not only increased the 30 day survival rate of mice after exposed to a lethal dose of gamma radiation but also had significant radioprotective effects on the hematopoietic system, the immune system and DNA of mice exposed...

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Veröffentlicht in:	Radiation research 2014-12, Vol.182 (6), p.666-673
Hauptverfasser:	Wang, Kai, Li, Peng-Fei, Han, Chun-Guang, Du, Li, Liu, Chao, Hu, Ming, Lian, Shi-Jie, Liu, Yong-Xue
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Blood - drug effects Blood - metabolism Blood - radiation effects Body weight Bone marrow Bone Marrow - drug effects Bone Marrow - metabolism Bone Marrow - radiation effects CHO Cells Cricetinae Cricetulus Deoxyribonucleic acid DNA DNA - genetics DNA - metabolism DNA damage Dogs Dosage Drug Discovery Erythrocytes Exposure Gamma radiation Gamma rays Gamma Rays - adverse effects Hematologic Tests Immune system Ionizing radiation Irradiation Lethal dose Male Mice Micronucleus Tests Omega 6 fatty acids Pyrones - pharmacology Radiation damage Radiation dosage Radiation-Protective Agents - pharmacology Radiotherapy REGULAR ARTICLES Survival Survival Rate Whole-Body Irradiation - adverse effects
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