Highly sensitive electrochemical biosensor based on nonlinear hybridization chain reaction for DNA detection

In the present work we demonstrated an ultrasensitive detection platform for specific DNA based on nonlinear hybridization chain reaction (HCR) by triggering chain-branching growth of DNA dendrimers. HCR was initiated by target DNA (tDNA) and finally formed dendritic structure by self-assembly. The...

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Veröffentlicht in:	Biosensors & bioelectronics 2016-06, Vol.80, p.392-397
Hauptverfasser:	Jia, Liping, Shi, Shanshan, Ma, Rongna, Jia, Wenli, Wang, Huaisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzidines - chemistry Bioelectricity Biosensing Techniques - methods Biosensor Biosensors Biotechnology Chain reactions Deoxyribonucleic acid DNA DNA - analysis Electrochemical Techniques - methods Hydrogen Peroxide - chemistry Limit of Detection Nonlinear hybridization chain reaction Nonlinearity Nucleic Acid Hybridization - methods Oxidation-Reduction Platforms Self assembly
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