Synthesis and Antibacterial Activity of some New Quinoxaline-1,4-Dioxide Derivatives

Synthesis and Antibacterial Activity of some New Quinoxaline-1,4-Dioxide Derivatives

As a continuation of our research and with the aim of obtaining new antibacterial agents which can improve the current chemotherapeutic antibacterial treatments, a series of quinoxaline-1,4-di-N-oxide derivatives were synthesized and evaluated for antibacterial activity against bacterial growing in...

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Veröffentlicht in:Advanced Materials Research 2013-01, Vol.634-638, p.1376-1379
Hauptverfasser: Li, Xue Hu, Tao, Lei, Lu, Xi Hong, Xin, Zhi Jun, Liang, Jian Ping
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Sprache:eng
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Antiinfectives and antibacterials
Bacteria
Derivatives
In vitro testing
Macrophages
Synthesis
Toxicity
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container_title Advanced Materials Research
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creator Li, Xue Hu
Tao, Lei
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Xin, Zhi Jun
Liang, Jian Ping
description As a continuation of our research and with the aim of obtaining new antibacterial agents which can improve the current chemotherapeutic antibacterial treatments, a series of quinoxaline-1,4-di-N-oxide derivatives were synthesized and evaluated for antibacterial activity against bacterial growing in macrophages in vitro. The results indicate that the new compounds exhibited a good antibacterial activity. Also, the potency and low toxicity of these compounds make them valid leads for synthesizing new compounds that possess better activity.
doi_str_mv 10.4028/www.scientific.net/AMR.634-638.1376
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subjects Antiinfectives and antibacterials
Bacteria
Derivatives
In vitro testing
Macrophages
Synthesis
Toxicity
title Synthesis and Antibacterial Activity of some New Quinoxaline-1,4-Dioxide Derivatives
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