Magnetism-Enhanced Monolith-Based In-Tube Solid Phase Microextraction
Monolith-based in-tube solid phase microextraction (MB/IT-SPME) has received wide attention because of miniaturization, automation, expected loading capacity, and environmental friendliness. However, the unsatisfactory extraction efficiency becomes the main disadvantage of MB/IT-SPME. To overcome th...
Gespeichert in:
| Veröffentlicht in: | Analytical chemistry (Washington) 2016-02, Vol.88 (3), p.1900-1907 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1907 |
|---|---|
| container_issue | 3 |
| container_start_page | 1900 |
| container_title | Analytical chemistry (Washington) |
| container_volume | 88 |
| creator | Mei, Meng Huang, Xiaojia Luo, Qing Yuan, Dongxin |
| description | Monolith-based in-tube solid phase microextraction (MB/IT-SPME) has received wide attention because of miniaturization, automation, expected loading capacity, and environmental friendliness. However, the unsatisfactory extraction efficiency becomes the main disadvantage of MB/IT-SPME. To overcome this circumstance, magnetism-enhanced MB/IT-SPME (ME-MB/IT-SPME) was developed in the present work, taking advantage of magnetic microfluidic principles. First, modified Fe3O4 nanoparticles were mixed with polymerization solution and in situ polymerized in the capillary to obtain a magnetic monolith extraction phase. After that, the monolithic capillary column was placed inside a magnetic coil that allowed the exertion of a variable magnetic field. The effects of intensity of magnetic field, adsorption and desorption flow rate, volume of sample, and desorption solvent on the performance of ME-MB/IT-SPME were investigated in detail. The analysis of six steroid hormones in water samples by the combination of ME-MB/IT-SPME with high-performance liquid chromatography with diode array detection was selected as a paradigm for the practical evaluation of ME-MB/IT-SPME. The application of a controlled magnetic field resulted in an obvious increase of extraction efficiencies of the target analytes between 70% and 100%. The present work demonstrated that application of different magnetic forces in adsorption and desorption steps can effectively enhance extraction efficiency of MB/IT-SPME systems. |
| doi_str_mv | 10.1021/acs.analchem.5b04328 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1793253835</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3953120281</sourcerecordid><originalsourceid>FETCH-LOGICAL-a512t-46d3b52cab01e077e4b6ff5452a16a81a974a53e15c64d0f4cc56eccb92833f93</originalsourceid><addsrcrecordid>eNqNkV1LwzAUhoMobk7_gUjBG286Tz7bXuqYOthQcF6HNE1tR5vOpgX992ZuU_BCvAo5PO8bTh6EzjGMMRB8rbQbK6sqXZh6zFNglMQHaIg5gVDEMTlEQwCgIYkABujEuRUAxoDFMRoQETHCExii6UK9WtOVrg6ntlBWmyxYNLapyq4Ib5Xz15kNl31qgmc_zIKnwg-DRanbxrx3rdJd2dhTdJSrypmz3TlCL3fT5eQhnD_ezyY381BxTLqQiYymnGiVAjYQRYalIs8540RhoWKskogpTg3mWrAMcqY1F0brNCExpXlCR-hq27tum7feuE7WpdOmqpQ1Te8kjhJKOI0p_wcqCGU8imKPXv5CV03f-q_9ojimCcfCU2xL-c2da00u121Zq_ZDYpAbI9IbkXsjcmfExy525X1am-w7tFfgAdgCm_jPw391fgLdyZif</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1765139516</pqid></control><display><type>article</type><title>Magnetism-Enhanced Monolith-Based In-Tube Solid Phase Microextraction</title><source>American Chemical Society Journals</source><creator>Mei, Meng ; Huang, Xiaojia ; Luo, Qing ; Yuan, Dongxin</creator><creatorcontrib>Mei, Meng ; Huang, Xiaojia ; Luo, Qing ; Yuan, Dongxin</creatorcontrib><description>Monolith-based in-tube solid phase microextraction (MB/IT-SPME) has received wide attention because of miniaturization, automation, expected loading capacity, and environmental friendliness. However, the unsatisfactory extraction efficiency becomes the main disadvantage of MB/IT-SPME. To overcome this circumstance, magnetism-enhanced MB/IT-SPME (ME-MB/IT-SPME) was developed in the present work, taking advantage of magnetic microfluidic principles. First, modified Fe3O4 nanoparticles were mixed with polymerization solution and in situ polymerized in the capillary to obtain a magnetic monolith extraction phase. After that, the monolithic capillary column was placed inside a magnetic coil that allowed the exertion of a variable magnetic field. The effects of intensity of magnetic field, adsorption and desorption flow rate, volume of sample, and desorption solvent on the performance of ME-MB/IT-SPME were investigated in detail. The analysis of six steroid hormones in water samples by the combination of ME-MB/IT-SPME with high-performance liquid chromatography with diode array detection was selected as a paradigm for the practical evaluation of ME-MB/IT-SPME. The application of a controlled magnetic field resulted in an obvious increase of extraction efficiencies of the target analytes between 70% and 100%. The present work demonstrated that application of different magnetic forces in adsorption and desorption steps can effectively enhance extraction efficiency of MB/IT-SPME systems.</description><identifier>ISSN: 0003-2700</identifier><identifier>EISSN: 1520-6882</identifier><identifier>DOI: 10.1021/acs.analchem.5b04328</identifier><identifier>PMID: 26742590</identifier><identifier>CODEN: ANCHAM</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Adsorption ; Capillarity ; Chromatography ; Computational efficiency ; Computing time ; Desorption ; Extraction ; Magnetic fields ; Magnetism ; Nanoparticles ; Polymerization ; Solid phases ; Solids</subject><ispartof>Analytical chemistry (Washington), 2016-02, Vol.88 (3), p.1900-1907</ispartof><rights>Copyright © 2016 American Chemical Society</rights><rights>Copyright American Chemical Society Feb 2, 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a512t-46d3b52cab01e077e4b6ff5452a16a81a974a53e15c64d0f4cc56eccb92833f93</citedby><cites>FETCH-LOGICAL-a512t-46d3b52cab01e077e4b6ff5452a16a81a974a53e15c64d0f4cc56eccb92833f93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acs.analchem.5b04328$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acs.analchem.5b04328$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2752,27053,27901,27902,56713,56763</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26742590$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mei, Meng</creatorcontrib><creatorcontrib>Huang, Xiaojia</creatorcontrib><creatorcontrib>Luo, Qing</creatorcontrib><creatorcontrib>Yuan, Dongxin</creatorcontrib><title>Magnetism-Enhanced Monolith-Based In-Tube Solid Phase Microextraction</title><title>Analytical chemistry (Washington)</title><addtitle>Anal. Chem</addtitle><description>Monolith-based in-tube solid phase microextraction (MB/IT-SPME) has received wide attention because of miniaturization, automation, expected loading capacity, and environmental friendliness. However, the unsatisfactory extraction efficiency becomes the main disadvantage of MB/IT-SPME. To overcome this circumstance, magnetism-enhanced MB/IT-SPME (ME-MB/IT-SPME) was developed in the present work, taking advantage of magnetic microfluidic principles. First, modified Fe3O4 nanoparticles were mixed with polymerization solution and in situ polymerized in the capillary to obtain a magnetic monolith extraction phase. After that, the monolithic capillary column was placed inside a magnetic coil that allowed the exertion of a variable magnetic field. The effects of intensity of magnetic field, adsorption and desorption flow rate, volume of sample, and desorption solvent on the performance of ME-MB/IT-SPME were investigated in detail. The analysis of six steroid hormones in water samples by the combination of ME-MB/IT-SPME with high-performance liquid chromatography with diode array detection was selected as a paradigm for the practical evaluation of ME-MB/IT-SPME. The application of a controlled magnetic field resulted in an obvious increase of extraction efficiencies of the target analytes between 70% and 100%. The present work demonstrated that application of different magnetic forces in adsorption and desorption steps can effectively enhance extraction efficiency of MB/IT-SPME systems.</description><subject>Adsorption</subject><subject>Capillarity</subject><subject>Chromatography</subject><subject>Computational efficiency</subject><subject>Computing time</subject><subject>Desorption</subject><subject>Extraction</subject><subject>Magnetic fields</subject><subject>Magnetism</subject><subject>Nanoparticles</subject><subject>Polymerization</subject><subject>Solid phases</subject><subject>Solids</subject><issn>0003-2700</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNkV1LwzAUhoMobk7_gUjBG286Tz7bXuqYOthQcF6HNE1tR5vOpgX992ZuU_BCvAo5PO8bTh6EzjGMMRB8rbQbK6sqXZh6zFNglMQHaIg5gVDEMTlEQwCgIYkABujEuRUAxoDFMRoQETHCExii6UK9WtOVrg6ntlBWmyxYNLapyq4Ib5Xz15kNl31qgmc_zIKnwg-DRanbxrx3rdJd2dhTdJSrypmz3TlCL3fT5eQhnD_ezyY381BxTLqQiYymnGiVAjYQRYalIs8540RhoWKskogpTg3mWrAMcqY1F0brNCExpXlCR-hq27tum7feuE7WpdOmqpQ1Te8kjhJKOI0p_wcqCGU8imKPXv5CV03f-q_9ojimCcfCU2xL-c2da00u121Zq_ZDYpAbI9IbkXsjcmfExy525X1am-w7tFfgAdgCm_jPw391fgLdyZif</recordid><startdate>20160202</startdate><enddate>20160202</enddate><creator>Mei, Meng</creator><creator>Huang, Xiaojia</creator><creator>Luo, Qing</creator><creator>Yuan, Dongxin</creator><general>American Chemical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7U5</scope><scope>7U7</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20160202</creationdate><title>Magnetism-Enhanced Monolith-Based In-Tube Solid Phase Microextraction</title><author>Mei, Meng ; Huang, Xiaojia ; Luo, Qing ; Yuan, Dongxin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a512t-46d3b52cab01e077e4b6ff5452a16a81a974a53e15c64d0f4cc56eccb92833f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adsorption</topic><topic>Capillarity</topic><topic>Chromatography</topic><topic>Computational efficiency</topic><topic>Computing time</topic><topic>Desorption</topic><topic>Extraction</topic><topic>Magnetic fields</topic><topic>Magnetism</topic><topic>Nanoparticles</topic><topic>Polymerization</topic><topic>Solid phases</topic><topic>Solids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mei, Meng</creatorcontrib><creatorcontrib>Huang, Xiaojia</creatorcontrib><creatorcontrib>Luo, Qing</creatorcontrib><creatorcontrib>Yuan, Dongxin</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Analytical chemistry (Washington)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mei, Meng</au><au>Huang, Xiaojia</au><au>Luo, Qing</au><au>Yuan, Dongxin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetism-Enhanced Monolith-Based In-Tube Solid Phase Microextraction</atitle><jtitle>Analytical chemistry (Washington)</jtitle><addtitle>Anal. Chem</addtitle><date>2016-02-02</date><risdate>2016</risdate><volume>88</volume><issue>3</issue><spage>1900</spage><epage>1907</epage><pages>1900-1907</pages><issn>0003-2700</issn><eissn>1520-6882</eissn><coden>ANCHAM</coden><abstract>Monolith-based in-tube solid phase microextraction (MB/IT-SPME) has received wide attention because of miniaturization, automation, expected loading capacity, and environmental friendliness. However, the unsatisfactory extraction efficiency becomes the main disadvantage of MB/IT-SPME. To overcome this circumstance, magnetism-enhanced MB/IT-SPME (ME-MB/IT-SPME) was developed in the present work, taking advantage of magnetic microfluidic principles. First, modified Fe3O4 nanoparticles were mixed with polymerization solution and in situ polymerized in the capillary to obtain a magnetic monolith extraction phase. After that, the monolithic capillary column was placed inside a magnetic coil that allowed the exertion of a variable magnetic field. The effects of intensity of magnetic field, adsorption and desorption flow rate, volume of sample, and desorption solvent on the performance of ME-MB/IT-SPME were investigated in detail. The analysis of six steroid hormones in water samples by the combination of ME-MB/IT-SPME with high-performance liquid chromatography with diode array detection was selected as a paradigm for the practical evaluation of ME-MB/IT-SPME. The application of a controlled magnetic field resulted in an obvious increase of extraction efficiencies of the target analytes between 70% and 100%. The present work demonstrated that application of different magnetic forces in adsorption and desorption steps can effectively enhance extraction efficiency of MB/IT-SPME systems.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>26742590</pmid><doi>10.1021/acs.analchem.5b04328</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2700 |
| ispartof | Analytical chemistry (Washington), 2016-02, Vol.88 (3), p.1900-1907 |
| issn | 0003-2700 1520-6882 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1793253835 |
| source | American Chemical Society Journals |
| subjects | Adsorption Capillarity Chromatography Computational efficiency Computing time Desorption Extraction Magnetic fields Magnetism Nanoparticles Polymerization Solid phases Solids |
| title | Magnetism-Enhanced Monolith-Based In-Tube Solid Phase Microextraction |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T00%3A40%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Magnetism-Enhanced%20Monolith-Based%20In-Tube%20Solid%20Phase%20Microextraction&rft.jtitle=Analytical%20chemistry%20(Washington)&rft.au=Mei,%20Meng&rft.date=2016-02-02&rft.volume=88&rft.issue=3&rft.spage=1900&rft.epage=1907&rft.pages=1900-1907&rft.issn=0003-2700&rft.eissn=1520-6882&rft.coden=ANCHAM&rft_id=info:doi/10.1021/acs.analchem.5b04328&rft_dat=%3Cproquest_cross%3E3953120281%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1765139516&rft_id=info:pmid/26742590&rfr_iscdi=true |