On-Chip Mesoporous Functionalized Magnetic Microspheres for Protein Sequencing by Extended Bottom-up Mass Spectrometry

A limited amount and extreme concentration variability of proteomic-related samples require efficient analyte preconcentration and purification prior to the mass spectrometry (MS)-based analysis. Preferably, these steps should be coupled online with chosen fractionation and detection techniques for...

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Veröffentlicht in:Analytical chemistry (Washington) 2016-02, Vol.88 (3), p.1775-1784
Hauptverfasser: Gasilova, Natalia, Srzentić, Kristina, Qiao, Liang, Liu, Baohong, Beck, Alain, Tsybin, Yury O, Girault, Hubert H
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Sprache:eng
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