Prevalence of gestational diabetes and risk of complications before and after initiation of a general systematic two-step screening strategy in Germany (2012–2014)

Abstract Aims Information on the prevalence of gestational diabetes mellitus is scarce on national and international level. On July 1st, 2013, a general two-step screening was implemented in Germany harmonizing gestational diabetes diagnoses. We aim to provide prevalence estimates for gestational di...

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Veröffentlicht in:Diabetes research and clinical practice 2016-05, Vol.115, p.1-8
Hauptverfasser: Tamayo, T, Tamayo, M, Rathmann, W, Potthoff, P
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creator Tamayo, T
Tamayo, M
Rathmann, W
Potthoff, P
description Abstract Aims Information on the prevalence of gestational diabetes mellitus is scarce on national and international level. On July 1st, 2013, a general two-step screening was implemented in Germany harmonizing gestational diabetes diagnoses. We aim to provide prevalence estimates for gestational diabetes and pregnancy-related complications for the large region of North Rhine for the 12 months before and after introduction of the general screening. Methods Routine care data covering all outpatient diagnoses of more than 150,000 pregnancies per 12-month period in women aged 15–55 years was used to determine cases of gestational diabetes. Gestational diabetes diagnosis and pregnancy-related complications were assessed according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10). Relative Risks for pregnancy-related complications were calculated in pregnancies with and without gestational diabetes. Results Before the screening, diagnosis of gestational diabetes was made in 6.02% of pregnancies and in 6.81% after this date (other types of diabetes mellitus: 1.67% and 1.76% respectively). The prevalence of GDM increased with age and was highest at age 36–40 years (8.45%). The relative increase in prevalence after introduction of the screening was highest in the age group ≤ 25 years (24.9%). The frequency of pregnancy-related complications such as hypertension, pre-eclampsia, cesarean section was increased in pregnancies with gestational diabetes in comparison to those without independent of observation period. Conclusions We found a high prevalence of gestational diabetes, which has relatively increased by 13.12% after the introduction of the general screening.
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On July 1st, 2013, a general two-step screening was implemented in Germany harmonizing gestational diabetes diagnoses. We aim to provide prevalence estimates for gestational diabetes and pregnancy-related complications for the large region of North Rhine for the 12 months before and after introduction of the general screening. Methods Routine care data covering all outpatient diagnoses of more than 150,000 pregnancies per 12-month period in women aged 15–55 years was used to determine cases of gestational diabetes. Gestational diabetes diagnosis and pregnancy-related complications were assessed according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10). Relative Risks for pregnancy-related complications were calculated in pregnancies with and without gestational diabetes. Results Before the screening, diagnosis of gestational diabetes was made in 6.02% of pregnancies and in 6.81% after this date (other types of diabetes mellitus: 1.67% and 1.76% respectively). The prevalence of GDM increased with age and was highest at age 36–40 years (8.45%). The relative increase in prevalence after introduction of the screening was highest in the age group ≤ 25 years (24.9%). The frequency of pregnancy-related complications such as hypertension, pre-eclampsia, cesarean section was increased in pregnancies with gestational diabetes in comparison to those without independent of observation period. Conclusions We found a high prevalence of gestational diabetes, which has relatively increased by 13.12% after the introduction of the general screening.</description><identifier>ISSN: 0168-8227</identifier><identifier>EISSN: 1872-8227</identifier><identifier>DOI: 10.1016/j.diabres.2016.03.001</identifier><identifier>PMID: 27242116</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Adolescent ; Adult ; Diabetes, Gestational - diagnosis ; Diabetes, Gestational - epidemiology ; Endocrinology &amp; Metabolism ; Female ; Germany - epidemiology ; Gestational diabetes ; Glucose Tolerance Test ; Humans ; Mass Screening ; Middle Aged ; Nationwide strategy ; Oral glucose tolerance test ; Pre-Eclampsia - diagnosis ; Pre-Eclampsia - epidemiology ; Pregnancy ; Pregnancy Outcome ; Pregnancy-related complications ; Prevalence ; Risk Factors ; Routine care ; Two-step screening ; Young Adult</subject><ispartof>Diabetes research and clinical practice, 2016-05, Vol.115, p.1-8</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2016 Elsevier Ireland Ltd</rights><rights>Copyright © 2016 Elsevier Ireland Ltd. 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On July 1st, 2013, a general two-step screening was implemented in Germany harmonizing gestational diabetes diagnoses. We aim to provide prevalence estimates for gestational diabetes and pregnancy-related complications for the large region of North Rhine for the 12 months before and after introduction of the general screening. Methods Routine care data covering all outpatient diagnoses of more than 150,000 pregnancies per 12-month period in women aged 15–55 years was used to determine cases of gestational diabetes. Gestational diabetes diagnosis and pregnancy-related complications were assessed according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10). Relative Risks for pregnancy-related complications were calculated in pregnancies with and without gestational diabetes. Results Before the screening, diagnosis of gestational diabetes was made in 6.02% of pregnancies and in 6.81% after this date (other types of diabetes mellitus: 1.67% and 1.76% respectively). The prevalence of GDM increased with age and was highest at age 36–40 years (8.45%). The relative increase in prevalence after introduction of the screening was highest in the age group ≤ 25 years (24.9%). The frequency of pregnancy-related complications such as hypertension, pre-eclampsia, cesarean section was increased in pregnancies with gestational diabetes in comparison to those without independent of observation period. 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On July 1st, 2013, a general two-step screening was implemented in Germany harmonizing gestational diabetes diagnoses. We aim to provide prevalence estimates for gestational diabetes and pregnancy-related complications for the large region of North Rhine for the 12 months before and after introduction of the general screening. Methods Routine care data covering all outpatient diagnoses of more than 150,000 pregnancies per 12-month period in women aged 15–55 years was used to determine cases of gestational diabetes. Gestational diabetes diagnosis and pregnancy-related complications were assessed according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10). Relative Risks for pregnancy-related complications were calculated in pregnancies with and without gestational diabetes. Results Before the screening, diagnosis of gestational diabetes was made in 6.02% of pregnancies and in 6.81% after this date (other types of diabetes mellitus: 1.67% and 1.76% respectively). The prevalence of GDM increased with age and was highest at age 36–40 years (8.45%). The relative increase in prevalence after introduction of the screening was highest in the age group ≤ 25 years (24.9%). The frequency of pregnancy-related complications such as hypertension, pre-eclampsia, cesarean section was increased in pregnancies with gestational diabetes in comparison to those without independent of observation period. Conclusions We found a high prevalence of gestational diabetes, which has relatively increased by 13.12% after the introduction of the general screening.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>27242116</pmid><doi>10.1016/j.diabres.2016.03.001</doi><tpages>8</tpages></addata></record>
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subjects Adolescent
Adult
Diabetes, Gestational - diagnosis
Diabetes, Gestational - epidemiology
Endocrinology & Metabolism
Female
Germany - epidemiology
Gestational diabetes
Glucose Tolerance Test
Humans
Mass Screening
Middle Aged
Nationwide strategy
Oral glucose tolerance test
Pre-Eclampsia - diagnosis
Pre-Eclampsia - epidemiology
Pregnancy
Pregnancy Outcome
Pregnancy-related complications
Prevalence
Risk Factors
Routine care
Two-step screening
Young Adult
title Prevalence of gestational diabetes and risk of complications before and after initiation of a general systematic two-step screening strategy in Germany (2012–2014)
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