Genetic Variants of Thymic Stromal Lymphopoietin in Nonsteroidal Anti-Inflammatory Drug-Induced Urticaria/Angioedema

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequent agents involved in hypersensitivity drug reactions, with NSAID-induced urticaria and/or angioedema (NIUA) being the most common entity. Mast cells are key players in NIUA and are activated by thymic stromal lymphopoietin...

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Veröffentlicht in:	International archives of allergy and immunology 2016-01, Vol.169 (4), p.249-255
Hauptverfasser:	Plaza-Serón, María del Carmen, Blanca-López, Natalia, Pérez-Sánchez, Natalia, Doña, Inmaculada, Acosta-Herrera, Marialbert, Pino-Yanes, María, Flores, Carlos, Cornejo-García, José Antonio, Perkins, James R., Molina, Ana, Torres, Maria José, Blanca, Miguel, Canto, María Gabriela, Ayuso, Pedro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Analysis Angioedema Angioedema - diagnosis Angioneurotic edema Anti-Inflammatory Agents, Non-Steroidal - adverse effects Case-Control Studies Cellular biology Complications and side effects Cytokines Cytokines - genetics Development and progression Drug hypersensitivity Drug Hypersensitivity - diagnosis Drug Hypersensitivity - etiology Female Genetic aspects Genetic Predisposition to Disease Genetic Variation Genotype Health aspects Hives (Disease) Humans Male Middle Aged Nonsteroidal anti-inflammatory agents Nonsteroidal anti-inflammatory drugs Odds Ratio Original Paper Polymorphism, Single Nucleotide Side effects Single nucleotide polymorphisms Thymic stromal lymphopoietin Urticaria - diagnosis Young Adult
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