Cell Cycle-dependent Phosphorylation of the DNA Polymerase Epsilon Subunit, Dpb2, by the Cdc28 Cyclin-dependent Protein Kinase

DNA polymerase ϵ (Polϵ), one of the three major eukaryotic replicative polymerases, is comprised of the essential catalytic subunit, called Pol2 in budding yeast, and three accessory subunits, only one of which, Dpb2, is essential. Polϵ is recruited to replication origins during late G 1 phase pr...

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Veröffentlicht in:	The Journal of biological chemistry 2004-04, Vol.279 (14), p.14245-14255
Hauptverfasser:	Kesti, Tapio, McDonald, W Hayes, Yates, 3rd, John R, Wittenberg, Curt
Format:	Artikel
Sprache:	eng
Schlagworte:	CDC28 Protein Kinase, S cerevisiae - metabolism Cell Cycle - physiology DNA Polymerase II - genetics DNA Polymerase II - metabolism DNA Replication Mutation Phenotype Phosphorylation Saccharomyces cerevisiae Saccharomycetales - cytology Saccharomycetales - enzymology Saccharomycetales - genetics
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