An R111C Polymorphism in Wild Turkey Cardiac Troponin I Accompanying the Dilated Cardiomyopathy-related Abnormal Splicing Variant of Cardiac Troponin T with Potentially Compensatory Effects

Cardiac muscle contraction is regulated by Ca 2+ through the troponin complex consisting of three subunits: troponin C (TnC), troponin T (TnT), and troponin I (TnI). We reported previously that the abnormal splicing of cardiac TnT in turkeys with dilated cardiomyopathy resulted in a greater binding...

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Veröffentlicht in:The Journal of biological chemistry 2004-04, Vol.279 (14), p.13825-13832
Hauptverfasser: Biesiadecki, Brandon J, Schneider, Kristi L, Yu, Zhi-Bin, Chong, Stephen M, Jin, Jian-Ping
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Sprache:eng
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