White Matter Hyperintensities Are Under Strong Genetic Influence

BACKGROUND AND PURPOSE—The genetic basis of white matter hyperintensities (WMH) is still unknown. This study examines the heritability of WMH in both sexes and in different brain regions, and the influence of age. METHODS—Participants from the Older Australian Twins Study were recruited (n=320; 92 m...

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Veröffentlicht in:	Stroke (1970) 2016-06, Vol.47 (6), p.1422-1428
Hauptverfasser:	Sachdev, Perminder S, Thalamuthu, Anbupalam, Mather, Karen A, Ames, David, Wright, Margaret J, Wen, Wei, Bowden, Jocelyn, Lee, Teresa, Brodaty, Henry, Crawford, John, Duckworth, Tanya, Kang, Kristan, Garden, Natalie, Martin, Nick, Lemmon, Christel
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aging - pathology Australia - epidemiology Brain Diseases - diagnostic imaging Brain Diseases - epidemiology Cerebellum - diagnostic imaging Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Middle Aged Occipital Lobe - diagnostic imaging Sex Characteristics White Matter - diagnostic imaging
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