Unfermented grape juice reduce genomic damage on patients undergoing hemodialysis

Chronic kidney disease (CKD) patients in dialysis (HD) are considered to be submitted to a continuous oxidative stress. This stress can cause damage on DNA and, consequently, contribute to the high levels of DNA damage observed in these patients. Due to the well-known role of polyphenols as antioxid...

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Veröffentlicht in:	Food and chemical toxicology 2016-06, Vol.92, p.1-7
Hauptverfasser:	Corredor, Zuray, Rodríguez-Ribera, Lara, Coll, Elisabeth, Montañés, Rosario, Diaz, Juan Manuel, Ballarin, José, Marcos, Ricard, Pastor, Susana
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants - pharmacology Beverages Comet Assay Dietary Supplements DNA Damage - drug effects DNA Damage - genetics Female Genomics - methods Hemodialysis Humans Male Micronucleus assay Micronucleus Tests Middle Aged Oxidation-Reduction Oxidative damage Oxidative Stress - drug effects Polyphenols - pharmacology Renal Dialysis - adverse effects Renal Insufficiency, Chronic - genetics Renal Insufficiency, Chronic - pathology Trolox equivalent antioxidant capacity (TEAC) assay Unfermented grape juice (UGJ) Vitaceae Vitis - chemistry
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