Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder

Cross-sectional neuroimaging studies in non-depressed individuals have demonstrated an inverse relationship between daylight minutes and cerebral serotonin transporter; this relationship is modified by serotonin-transporter-linked polymorphic region short allele carrier status. We here present data...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2016-05, Vol.139 (Pt 5), p.1605-1614
Hauptverfasser:	Mc Mahon, Brenda, Andersen, Sofie B, Madsen, Martin K, Hjordt, Liv V, Hageman, Ida, Dam, Henrik, Svarer, Claus, da Cunha-Bang, Sofi, Baaré, William, Madsen, Jacob, Hasholt, Lis, Holst, Klaus, Frokjaer, Vibe G, Knudsen, Gitte M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Benzylamines - metabolism Carbon Radioisotopes - metabolism Case-Control Studies Estradiol - blood Female Humans Longitudinal Studies Male Neuroimaging Positron-Emission Tomography Progesterone Psychiatric Status Rating Scales Radioligand Assay Seasonal Affective Disorder - diagnosis Seasonal Affective Disorder - diagnostic imaging Seasonal Affective Disorder - metabolism Seasons Serotonin Plasma Membrane Transport Proteins - metabolism Tryptophan - blood Young Adult
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