Somatic CPEB4 and CPEB1 genes mutations spectrum on the prognostic predictive accuracy in patients with high-grade glioma and their clinical significance

Abstract Background Glioblastoma (grade IV glioma/GBM) is characterized by extremely aggressive invasion and proliferative nature. Objective The main goal of this study was to evaluate the expression patterns of CPEB1 and CPEB4 in glioma patients. Methods 41 paraffin-embedded tissue samples with gli...

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Veröffentlicht in:	Journal of the neurological sciences 2016-04, Vol.363, p.80-83
Hauptverfasser:	Boustani, Mohammad Reza, Mehrabi, Farzad, Yahaghi, Emad, Khoshnood, Reza Jalili, Shahmohammadi, Mohammadreza, Darian, Ebrahim Khodaveri, Goudarzi, Peyman Karimi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Biomarker Biomarkers, Tumor - genetics Brain Neoplasms - diagnosis Brain Neoplasms - genetics Brain Neoplasms - mortality Female Follow-Up Studies Glioma Glioma - diagnosis Glioma - genetics Glioma - mortality Humans IHC Male Middle Aged mRNA Cleavage and Polyadenylation Factors - genetics Mutation - genetics Neurology Patient PCR Predictive Value of Tests Prognosis RNA-Binding Proteins - genetics Survival Survival Rate - trends Transcription Factors - genetics
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