Acoustic Cluster Therapy: In Vitro and Ex Vivo Measurement of Activated Bubble Size Distribution and Temporal Dynamics

Abstract Acoustic cluster technology (ACT) is a two-component, microparticle formulation platform being developed for ultrasound-mediated drug delivery. Sonazoid microbubbles, which have a negative surface charge, are mixed with micron-sized perfluoromethylcyclopentane droplets stabilized with a pos...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Ultrasound in medicine & biology 2016-05, Vol.42 (5), p.1145-1166
Hauptverfasser:	Healey, Andrew John, Sontum, Per Christian, Kvåle, Svein, Eriksen, Morten, Bendiksen, Ragnar, Tornes, Audun, Østensen, Jonny
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic cluster therapy Animals Blood Chemical Analysis Contrast Media - chemistry Contrast Media - radiation effects Delayed-Action Preparations Dogs Dose-Response Relationship, Radiation Droplet vaporization Ex vivo bubble sizing Ferric Compounds - blood Ferric Compounds - chemistry Ferric Compounds - radiation effects Gases - chemical synthesis Gases - radiation effects High-Energy Shock Waves In vitro bubble sizing In vivo bubble sizing Iron - blood Iron - chemistry Iron - radiation effects Male Microbubbles Myocardial perfusion imaging Oxides - blood Oxides - chemistry Oxides - radiation effects Particle Size Radiation Dosage Radiology Sonication - methods Ultrasound contrast agent
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!