Capsid-like supramolecular dendritic systems as pH-responsive nanocarriers for drug penetration and site-specific delivery

Abstract Supramolecular dendritic systems emerge as a promising new-generation bioinspired nanoplatform for nanomedicine. Herein, we report capsid-like mimics self-assembled from peptide dendrimers and functionalized peptides to enhance drug penetration and site-specific delivery for tumor therapy....

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Veröffentlicht in:	Nanomedicine 2016-02, Vol.12 (2), p.355-364
Hauptverfasser:	Li, Yachao, BS, Lai, Yusi, PhD, Xu, Xianghui, PhD, Zhang, Xiao, MS, Wu, Yahui, MS, Hu, Cheng, BS, Gu, MS, Zhongwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, Antineoplastic - administration & dosage Antibiotics, Antineoplastic - pharmacokinetics Antibiotics, Antineoplastic - therapeutic use Bioinspired nanocarriers Breast - drug effects Breast - pathology Breast Neoplasms - drug therapy Breast Neoplasms - pathology Capsid - chemistry Delayed-Action Preparations - chemistry Dendrimers - chemistry Doxorubicin - administration & dosage Doxorubicin - pharmacokinetics Doxorubicin - therapeutic use Drug Delivery Systems - methods Drug penetration Female Hydrogen-Ion Concentration Internal Medicine Mice, Inbred BALB C Nanostructures - chemistry Nanostructures - ultrastructure pH-responsive controlled release Polylysine - chemistry Site-specific delivery Supramolecular dendritic system
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