T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model

The exact pathophysiology of major depressive disorder (MDD) remains elusive. The monoamine theory, which hypothesizes that MDD emerges as a result of dysfunctional serotonergic, dopaminergic and noradrenergic pathways, has guided the therapy of this illness for several decades. More recently, the i...

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Veröffentlicht in:	Neuroscience and biobehavioral reviews 2016-05, Vol.64, p.83-100
Hauptverfasser:	Slyepchenko, Anastasiya, Maes, Michael, Köhler, Cristiano A, Anderson, George, Quevedo, João, Alves, Gilberto S, Berk, Michael, Fernandes, Brisa S, Carvalho, André F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Depressive Disorder, Major - immunology Humans Th17 Cells - physiology
Online-Zugang:	Volltext
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