Mechanical stress models of Alzheimer's disease pathology

Abstract Introduction Extracellular accumulation of amyloid-β protein and intracellular accumulation of tau in brain tissues have been described in animal models of Alzheimer's disease (AD) and mechanical stress-based diseases of different mechanisms, such as traumatic brain injury (TBI), arter...

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Veröffentlicht in:	Alzheimer's & dementia 2016-03, Vol.12 (3), p.324-333
Hauptverfasser:	Levy Nogueira, Marcel, Epelbaum, Stéphane, Steyaert, Jean-Marc, Dubois, Bruno, Schwartz, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - pathology Alzheimer Disease - physiopathology Alzheimer's disease Amyloid beta-Peptides - genetics Amyloid beta-Peptides - metabolism Amyloid pathology Animal models Animals Animals, Genetically Modified Brain - pathology Brain injury Disease Models, Animal Humans Hypertension Mechanical stress Neurology Normal pressure hydrocephalus Stress, Mechanical tau Proteins - genetics tau Proteins - metabolism Tauopathy
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