Swine alveolar macrophage cell model allows optimal replication of influenza A viruses regardless of their origin

Abstract The importance of pigs in interspecies transmission of influenza A viruses has been repeatedly demonstrated over the last century. Eleven influenza A viruses from avian, human and swine hosts were evaluated for replication phenotypes at three physiologically relevant temperatures (41 °C, 37...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2016-03, Vol.490, p.91-98
Hauptverfasser:	Kasloff, Samantha B, Weingartl, Hana M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveolar macrophages Animals Birds Humans In vitro model Infectious Disease Influenza A virus - genetics Influenza A virus - isolation & purification Influenza A virus - physiology Influenza in Birds - immunology Influenza in Birds - virology Influenza virus Influenza, Human - virology Macrophages, Alveolar - immunology Macrophages, Alveolar - virology Orthomyxoviridae Infections - immunology Orthomyxoviridae Infections - veterinary Orthomyxoviridae Infections - virology Pigs Swine Swine Diseases - immunology Swine Diseases - virology Temperature sensitivity Tumor Necrosis Factor-alpha - immunology Virus Cultivation Virus Replication
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