Genotoxicity assessment of intravenously injected titanium dioxide nanoparticles in gpt delta transgenic mice

Titanium dioxide (TiO2) nanoparticles are increasingly manufactured in large amounts for use in industrial applications such as cosmetics, pigments, foods, and as photo-catalysts. Many in vitro studies have examined the genotoxicity of TiO2 nanomaterials; some of these studies suggest that TiO2 nano...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2016-05, Vol.802, p.30-37
Hauptverfasser:	Suzuki, Tetsuya, Miura, Nobuhiko, Hojo, Rieko, Yanagiba, Yukie, Suda, Megumi, Hasegawa, Tatsuya, Miyagawa, Muneyuki, Wang, Rui-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemical compounds DNA - drug effects DNA damage DNA Damage - drug effects DNA Damage - genetics gpt delta mice Male Metal Nanoparticles - toxicity Mice Mice, Inbred C57BL Mice, Transgenic Micronuclei Micronucleus Tests Mutation Mutation frequency Nanoparticles Rodents Titanium - toxicity Titanium dioxide Toxicity Transgenic animals
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