Introduction of a bacterial acetyl-CoA synthesis pathway improves lactic acid production in Saccharomyces cerevisiae

Acid-tolerant Saccharomyces cerevisiae was engineered to produce lactic acid by expressing heterologous lactate dehydrogenase (LDH) genes, while attenuating several key pathway genes, including glycerol-3-phosphate dehydrogenase1 (GPD1) and cytochrome-c oxidoreductase2 (CYB2). In order to increase t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Metabolic engineering 2016-05, Vol.35, p.38-45
Hauptverfasser:	Song, Ji-Yoon, Park, Joon-Song, Kang, Chang Duk, Cho, Hwa-Young, Yang, Dongsik, Lee, Seunghyun, Cho, Kwang Myung
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl Coenzyme A - biosynthesis Acetyl Coenzyme A - genetics Acetyl-CoA Acetylating acetaldehyde dehydrogenase Alcohol dehydrogenase Aldehyde Oxidoreductases - biosynthesis Aldehyde Oxidoreductases - genetics Bacteria Escherichia Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli Proteins - biosynthesis Escherichia coli Proteins - genetics Lactic acid Lactic Acid - biosynthesis Metabolic engineering Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!