Dextran-b-poly(lactide-co-glycolide) polymersome for oral delivery of insulin: In vitro and in vivo evaluation

Insulin is the first line therapy in type 1 diabetes and usually patients suffer from three or more daily insulin injections. It is obvious that patient compliance can be improved greatly if insulin could be formulated in an oral dosage form. In the current study, polymersomes based on amphiphilic c...

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Veröffentlicht in:Journal of controlled release 2016-04, Vol.227, p.58-70
Hauptverfasser: Alibolandi, Mona, Alabdollah, Fatemeh, Sadeghi, Fatemeh, Mohammadi, Marzieh, Abnous, Khalil, Ramezani, Mohammad, Hadizadeh, Farzin
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Sprache:eng
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