Molecular cloning, characterization and expression analysis of (B-cell lymphoma-2 associated X protein) Bax in the orange-spotted grouper (Epinephelus coioides) after the Vibrio alginolyticus challenge

Bax is a pro-apoptotic member of Bcl-2 like superfamily, playing an important role in regulating the apoptosis. In this study, the full-length Bax (EcBax) was obtained, containing a 5′UTR of 64 bp, an ORF of 579 bp and a 3′UTR of 1021 bp. The EcBax gene encoded a polypeptide of 192 amino acids with...

Ausführliche Beschreibung