The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis

Tumor vessels are known to be abnormal, with typically aberrant, leaky and disordered vessels. Here, we investigated whether polarized macrophage phenotypes are involved in tumor abnormal angiogenesis and what is its mechanism. We found that there was no difference in chemotaxis of polarized M1 and...

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Veröffentlicht in:Developmental and comparative immunology 2016-06, Vol.59, p.89-98
Hauptverfasser: Li, G.-G., Guo, Z.-Z., Ma, X.-F., Cao, N., Geng, S.-N., Zheng, Y.-Q., Meng, M.-J., Lin, H.-H., Han, G., Du, G.-J.
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