A Novel Secreted Form of Immune Suppressor Factor with High Homology to Vacuolar ATPases Identified by a Forward Genetic Approach of Functional Screening Based on Cell Proliferation

In the search for stromal-derived growth factors, we have identified a novel secreted short form of immune suppressor factor (ISF) using a combination of a genetic approach and retrovirus-mediated functional screening. This protein, which we termed ShIF, was isolated based on its ability to support...

Ausführliche Beschreibung