New insights into the role of the Brdt protein in the regulation of development and spermatogenesis in the mouse

The bromodomain testis-specific (BRDT) protein belongs to the bromodomain extra-terminal (BET) family of proteins. It serves as a transcriptional regulator of gene expression during spermatogenesis, and is an essential factor for the normal spermatogenesis process. In this study, we characterized mi...

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Veröffentlicht in:	Gene Expression Patterns 2016-03, Vol.20 (2), p.130-137
Hauptverfasser:	Barda, Shimi, Yogev, Leah, Paz, Gedalia, Yavetz, Haim, Hauser, Ron, Breitbart, Haim, Kleiman, Sandra E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brdt Bromodomain Gene Expression Regulation, Developmental - genetics Humans Infertility Male Mice Mice, Knockout Nuclear Proteins - biosynthesis Nuclear Proteins - genetics Pituitary-Adrenal System - growth & development Pituitary-Adrenal System - metabolism Spermatids - growth & development Spermatids - metabolism Spermatocytes - growth & development Spermatocytes - pathology Spermatogenesis Spermatogenesis - genetics Testis - growth & development Testis - metabolism
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