Agonistic and antagonistic activities of chemokines

Since the discovery of interleukin‐8, about 50 chemokines have been identified and characterized. Originally, they were considered as inducible mediators of inflammation, but in recent years, several chemokines were identified that are expressed constitutively and function in physiological traffic a...

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Veröffentlicht in:	Journal of leukocyte biology 2001-06, Vol.69 (6), p.881-884
Hauptverfasser:	Loetscher, Pius, Clark‐Lewis, Ian
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs chemokine receptors Chemokines - chemistry Chemokines - pharmacology Chemokines - physiology chemotaxis Chemotaxis, Leukocyte - drug effects Chemotaxis, Leukocyte - physiology GTP-Binding Proteins - physiology guanine nucleotide-binding protein Humans inflammation Leukocytes - cytology Leukocytes - drug effects Models, Biological natural antagonists Protein Binding Protein Structure, Tertiary Receptors, Chemokine - agonists Receptors, Chemokine - antagonists & inhibitors Receptors, Chemokine - chemistry Receptors, Chemokine - physiology Structure-Activity Relationship
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