A photic visual cycle of rhodopsin regeneration is dependent on Rgr

During visual excitation, rhodopsin undergoes photoactivation and bleaches to opsin and all-trans-retinal. To regenerate rhodopsin and maintain normal visual sensitivity, the all-trans isomer must be metabolized and reisomerized to produce the chromophore 11-cis-retinal in biochemical steps that con...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature genetics 2001-07, Vol.28 (3), p.256-260
Hauptverfasser:	Fong, Henry K.W, Chen, Pu, Hao, Wenshan, Rife, Lawrence, Wang, Xiao Peng, Shen, Daiwei, Chen, Jeannie, Ogden, Thomas, Van Boemel, Gretchen B, Wu, Lanyin, Yang, Mao
Format:	Artikel
Sprache:	eng
Schlagworte:	11-cis-Retinal Adaptation Animals Biological and medical sciences Cell physiology Classical genetics, quantitative genetics, hybrids Darkness Dose-Response Relationship, Radiation Electroretinography Eye - metabolism Eye - radiation effects Eye Proteins - genetics Eye Proteins - metabolism Fundamental and applied biological sciences. Psychology Genetic aspects Genetics of eukaryotes. Biological and molecular evolution Irradiation Light Mice Mice, Mutant Strains Models, Chemical Molecular and cellular biology Mutation Neurosciences Photic Stimulation Photoactivation Photobiology Physiological aspects pigment epithelium Proteins Publishing Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Receptors, G-Protein-Coupled retinal pigment epithelium Retinal Rod Photoreceptor Cells - metabolism Retinal Rod Photoreceptor Cells - radiation effects Retinaldehyde - metabolism Rgr gene Rhodopsin Rhodopsin - metabolism Rhodopsin - radiation effects Vertebrata Vision, photoreception
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!