Identification of CpG islands hypermethylated in human lung cancer by the arbitrarily primed-PCR method

DNA hypermethylation is believed to be involved in human carcinogenesis, since it suppresses the transcription of defined genes and is associated with chromosomal instability. In this study, we identified CpG islands that are hypermethylated in human lung cancer by a modified arbitrarily primed-poly...

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Veröffentlicht in:Human genetics 1998-03, Vol.102 (3), p.258-264
Hauptverfasser: KOHNO, T, KAWANISHI, M, INAZAWA, J, YOKOTA, J
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Sprache:eng
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