Single-Dose Pharmacokinetic Properties and Relative Bioavailability of a Novel Methylphenidate Extended-Release Chewable Tablet Compared With Immediate-Release Methylphenidate Chewable Tablet

Abstract Purpose A novel methylphenidate hydrochloride extended-release chewable tablet (MPH ERCT) was developed to potentially address an unmet need for patients with attention-deficit/hyperactivity disorder, especially children, who cannot or will not swallow tablets or would prefer the convenienc...

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Veröffentlicht in:	Clinical therapeutics 2016-05, Vol.38 (5), p.1151-1157
Hauptverfasser:	Abbas, Richat, PhD, Palumbo, Donna, PhD, Walters, Faith, PharmD, Belden, Heidi, PharmD, Berry, Sally A., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Area Under Curve Attention Deficit Hyperactivity Disorder Bioavailability Biological Availability Body mass index Cardiovascular disease Central Nervous System Stimulants - administration & dosage Central Nervous System Stimulants - pharmacokinetics Chemistry, Pharmaceutical Children & youth Clinical medicine Cross-Over Studies Delayed-Action Preparations dose forms Drug dosages Fasting Female Heart attacks Humans Hyperactivity Impulsivity Internal Medicine Male Medical Education methylphenidate Methylphenidate - administration & dosage Methylphenidate - pharmacokinetics Middle Aged pharmacokinetic properties Population Tablets Therapeutic Equivalency Young Adult
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