Reduced continuous-flow left ventricular assist device speed does not decrease von Willebrand factor degradation

Abstract Background Nonsurgical bleeding is a frequent complication of continuous-flow left ventricular assist device (LVAD) support. Abnormal von Willebrand factor (vWF) metabolism plays a major role. However, the relationship between LVAD speed and vWF degradation is unknown. Recent evidence has d...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2016-06, Vol.151 (6), p.1747-1754.e1
Hauptverfasser:	Kang, Jooeun, BA, Zhang, David M, Restle, David J., BSE, Kallel, Faouzi, PhD, Acker, Michael A., MD, Atluri, Pavan, MD, Bartoli, Carlo R., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged bleeding Cardiothoracic Surgery Electrophoresis, Polyacrylamide Gel Female heart failure Heart Failure - blood Heart Failure - complications Heart Failure - therapy Heart-Assist Devices Humans left ventricular assist device Male mechanical circulatory support Middle Aged shear stress Stress, Mechanical von Willebrand Diseases - blood von Willebrand Diseases - etiology von Willebrand factor von Willebrand Factor - analysis
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