Predictive value of low tube voltage and dual-energy CT for successful shock wave lithotripsy: an in vitro study
This study investigates the capabilities of low tube voltage computed tomography (CT) and dual-energy CT (DECT) for predicting successful shock wave lithotripsy (SWL) of urinary stones in vitro. A total of 33 urinary calculi (six different chemical compositions; mean size 6 ± 3 mm) were scanned usin...
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description | This study investigates the capabilities of low tube voltage computed tomography (CT) and dual-energy CT (DECT) for predicting successful shock wave lithotripsy (SWL) of urinary stones in vitro. A total of 33 urinary calculi (six different chemical compositions; mean size 6 ± 3 mm) were scanned using a dual-source CT machine with single- (120 kVp) and dual-energy settings (80/150, 100/150 Sn kVp) resulting in six different datasets. The attenuation (Hounsfield Units) of calculi was measured on single-energy CT images and the dual-energy indices (DEIs) were calculated from DECT acquisitions. Calculi underwent SWL and the number of shock waves for successful disintegration was recorded. The prediction of required shock waves regarding stone attenuation/DEI was calculated using regression analysis (adjusted for stone size and composition) and the correlation between CT attenuation/DEI and the number of shock waves was assessed for all datasets. The median number of shock waves for successful stone disintegration was 72 (interquartile range 30–361). CT attenuation/DEI of stones was a significant, independent predictor (
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doi_str_mv | 10.1007/s00240-015-0824-y |
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P
< 0.01) for the number of required shock waves with the best prediction at 80 kVp (
β
estimate 0.576) (
P
< 0.05). Correlation coefficients between attenuation/DEI and the number of required shock waves ranged between
ρ
= 0.31 and 0.68 showing the best correlation at 80 kVp (
P
< 0.001). The attenuation of urinary stones at low tube voltage CT is the best predictor for successful stone disintegration, being independent of stone composition and size. DECT shows no added value for predicting the success of SWL.</description><identifier>ISSN: 2194-7228</identifier><identifier>EISSN: 2194-7236</identifier><identifier>DOI: 10.1007/s00240-015-0824-y</identifier><identifier>PMID: 26391614</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Electric Power Supplies ; Humans ; In Vitro Techniques ; Lithotripsy ; Medical Biochemistry ; Medicine ; Medicine & Public Health ; Nephrology ; Original Paper ; Predictive Value of Tests ; Tomography, X-Ray Computed - methods ; Treatment Outcome ; Urinary Calculi - diagnostic imaging ; Urinary Calculi - therapy ; Urology</subject><ispartof>Urolithiasis, 2016-06, Vol.44 (3), p.271-276</ispartof><rights>Springer-Verlag Berlin Heidelberg 2015</rights><rights>Springer-Verlag Berlin Heidelberg 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-777d48a6b854213b1e70ea811ecc10e97a15c4afe747da0fe9d1f4db96ab01423</citedby><cites>FETCH-LOGICAL-c372t-777d48a6b854213b1e70ea811ecc10e97a15c4afe747da0fe9d1f4db96ab01423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00240-015-0824-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00240-015-0824-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26391614$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Largo, Remo</creatorcontrib><creatorcontrib>Stolzmann, Paul</creatorcontrib><creatorcontrib>Fankhauser, Christian D.</creatorcontrib><creatorcontrib>Poyet, Cédric</creatorcontrib><creatorcontrib>Wolfsgruber, Pirmin</creatorcontrib><creatorcontrib>Sulser, Tullio</creatorcontrib><creatorcontrib>Alkadhi, Hatem</creatorcontrib><creatorcontrib>Winklhofer, Sebastian</creatorcontrib><title>Predictive value of low tube voltage and dual-energy CT for successful shock wave lithotripsy: an in vitro study</title><title>Urolithiasis</title><addtitle>Urolithiasis</addtitle><addtitle>Urolithiasis</addtitle><description>This study investigates the capabilities of low tube voltage computed tomography (CT) and dual-energy CT (DECT) for predicting successful shock wave lithotripsy (SWL) of urinary stones in vitro. A total of 33 urinary calculi (six different chemical compositions; mean size 6 ± 3 mm) were scanned using a dual-source CT machine with single- (120 kVp) and dual-energy settings (80/150, 100/150 Sn kVp) resulting in six different datasets. The attenuation (Hounsfield Units) of calculi was measured on single-energy CT images and the dual-energy indices (DEIs) were calculated from DECT acquisitions. Calculi underwent SWL and the number of shock waves for successful disintegration was recorded. The prediction of required shock waves regarding stone attenuation/DEI was calculated using regression analysis (adjusted for stone size and composition) and the correlation between CT attenuation/DEI and the number of shock waves was assessed for all datasets. The median number of shock waves for successful stone disintegration was 72 (interquartile range 30–361). CT attenuation/DEI of stones was a significant, independent predictor (
P
< 0.01) for the number of required shock waves with the best prediction at 80 kVp (
β
estimate 0.576) (
P
< 0.05). Correlation coefficients between attenuation/DEI and the number of required shock waves ranged between
ρ
= 0.31 and 0.68 showing the best correlation at 80 kVp (
P
< 0.001). The attenuation of urinary stones at low tube voltage CT is the best predictor for successful stone disintegration, being independent of stone composition and size. DECT shows no added value for predicting the success of SWL.</description><subject>Electric Power Supplies</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Lithotripsy</subject><subject>Medical Biochemistry</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nephrology</subject><subject>Original Paper</subject><subject>Predictive Value of Tests</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Treatment Outcome</subject><subject>Urinary Calculi - diagnostic imaging</subject><subject>Urinary Calculi - therapy</subject><subject>Urology</subject><issn>2194-7228</issn><issn>2194-7236</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kU1r3DAQhkVpSUKSH5BLEfTSi1uNLFtWb2XpFwSaQ3oWsjTeONVaW31s8L-vwqahFDoXDdLzviPmJeQK2DtgTL5PjHHBGgZdwwYumvUFOeOgRCN527987vlwSi5Tume1lFIC2Ak55X2roAdxRvY3Ed1s83xAejC-IA0T9eGB5jLWm-Cz2SI1i6OuGN_ggnG70s0tnUKkqViLKU3F03QX7E_6YKqNn_NdyHHep_VDVdJ5oYc5x0BTLm69IK8m4xNePp3n5MfnT7ebr8319y_fNh-vG9tKnhsppROD6cehExzaEVAyNAMAWgsMlTTQWWEmlEI6wyZUDibhRtWbkYHg7Tl5e_Tdx_CrYMp6NyeL3psFQ0kapKoLhF50FX3zD3ofSlzq7yo1qHboGB8qBUfKxpBSxEnv47wzcdXA9GMi-piIronox0T0WjWvn5zLuEP3rPiz_wrwI5Dq07LF-Nfo_7r-BqpIlvs</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Largo, Remo</creator><creator>Stolzmann, Paul</creator><creator>Fankhauser, Christian D.</creator><creator>Poyet, Cédric</creator><creator>Wolfsgruber, Pirmin</creator><creator>Sulser, Tullio</creator><creator>Alkadhi, Hatem</creator><creator>Winklhofer, Sebastian</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20160601</creationdate><title>Predictive value of low tube voltage and dual-energy CT for successful shock wave lithotripsy: an in vitro study</title><author>Largo, Remo ; Stolzmann, Paul ; Fankhauser, Christian D. ; Poyet, Cédric ; Wolfsgruber, Pirmin ; Sulser, Tullio ; Alkadhi, Hatem ; Winklhofer, Sebastian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-777d48a6b854213b1e70ea811ecc10e97a15c4afe747da0fe9d1f4db96ab01423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Electric Power Supplies</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Lithotripsy</topic><topic>Medical Biochemistry</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nephrology</topic><topic>Original Paper</topic><topic>Predictive Value of Tests</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Treatment Outcome</topic><topic>Urinary Calculi - diagnostic imaging</topic><topic>Urinary Calculi - therapy</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Largo, Remo</creatorcontrib><creatorcontrib>Stolzmann, Paul</creatorcontrib><creatorcontrib>Fankhauser, Christian D.</creatorcontrib><creatorcontrib>Poyet, Cédric</creatorcontrib><creatorcontrib>Wolfsgruber, Pirmin</creatorcontrib><creatorcontrib>Sulser, Tullio</creatorcontrib><creatorcontrib>Alkadhi, Hatem</creatorcontrib><creatorcontrib>Winklhofer, Sebastian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Urolithiasis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Largo, Remo</au><au>Stolzmann, Paul</au><au>Fankhauser, Christian D.</au><au>Poyet, Cédric</au><au>Wolfsgruber, Pirmin</au><au>Sulser, Tullio</au><au>Alkadhi, Hatem</au><au>Winklhofer, Sebastian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictive value of low tube voltage and dual-energy CT for successful shock wave lithotripsy: an in vitro study</atitle><jtitle>Urolithiasis</jtitle><stitle>Urolithiasis</stitle><addtitle>Urolithiasis</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>44</volume><issue>3</issue><spage>271</spage><epage>276</epage><pages>271-276</pages><issn>2194-7228</issn><eissn>2194-7236</eissn><abstract>This study investigates the capabilities of low tube voltage computed tomography (CT) and dual-energy CT (DECT) for predicting successful shock wave lithotripsy (SWL) of urinary stones in vitro. A total of 33 urinary calculi (six different chemical compositions; mean size 6 ± 3 mm) were scanned using a dual-source CT machine with single- (120 kVp) and dual-energy settings (80/150, 100/150 Sn kVp) resulting in six different datasets. The attenuation (Hounsfield Units) of calculi was measured on single-energy CT images and the dual-energy indices (DEIs) were calculated from DECT acquisitions. Calculi underwent SWL and the number of shock waves for successful disintegration was recorded. The prediction of required shock waves regarding stone attenuation/DEI was calculated using regression analysis (adjusted for stone size and composition) and the correlation between CT attenuation/DEI and the number of shock waves was assessed for all datasets. The median number of shock waves for successful stone disintegration was 72 (interquartile range 30–361). CT attenuation/DEI of stones was a significant, independent predictor (
P
< 0.01) for the number of required shock waves with the best prediction at 80 kVp (
β
estimate 0.576) (
P
< 0.05). Correlation coefficients between attenuation/DEI and the number of required shock waves ranged between
ρ
= 0.31 and 0.68 showing the best correlation at 80 kVp (
P
< 0.001). The attenuation of urinary stones at low tube voltage CT is the best predictor for successful stone disintegration, being independent of stone composition and size. DECT shows no added value for predicting the success of SWL.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>26391614</pmid><doi>10.1007/s00240-015-0824-y</doi><tpages>6</tpages></addata></record> |
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subjects | Electric Power Supplies Humans In Vitro Techniques Lithotripsy Medical Biochemistry Medicine Medicine & Public Health Nephrology Original Paper Predictive Value of Tests Tomography, X-Ray Computed - methods Treatment Outcome Urinary Calculi - diagnostic imaging Urinary Calculi - therapy Urology |
title | Predictive value of low tube voltage and dual-energy CT for successful shock wave lithotripsy: an in vitro study |
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