p63α and ΔNp63α can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

The p53 tumor suppressor protein plays a critical role in the regulation of the cell cycle and apoptosis. The importance of p53's functions is underscored by the high incidence of p53 mutations in human cancers. Recently, two p53-related proteins, p73 and p63, were identified as members of the...

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