Establishment of a predicting model to evaluate the probability of malignancy or benign in patients with solid solitary pulmonary nodules

To develop a predicting model for evaluating the probability of malignancy or benign in patients with solid solitary pulmonary nodules through analyzing the clinical, radiologic, laboratory examination and radionuclide (18)F-Fluorodeoxyglucose examinations data. The data of the 203 patients(110 male...

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Veröffentlicht in:Zhong hua yi xue za zhi 2016-05, Vol.96 (17), p.1354-1358
Hauptverfasser: Xiang, Yangwei, Sun, Yifeng, Gao, Wen, Han, Baohui, Chen, Qunhui, Ye, Xiaodan, Zhu, Li, Liu, Yuan, Fang, Wentao
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container_end_page 1358
container_issue 17
container_start_page 1354
container_title Zhong hua yi xue za zhi
container_volume 96
creator Xiang, Yangwei
Sun, Yifeng
Gao, Wen
Han, Baohui
Chen, Qunhui
Ye, Xiaodan
Zhu, Li
Liu, Yuan
Fang, Wentao
description To develop a predicting model for evaluating the probability of malignancy or benign in patients with solid solitary pulmonary nodules through analyzing the clinical, radiologic, laboratory examination and radionuclide (18)F-Fluorodeoxyglucose examinations data. The data of the 203 patients(110 males and 93 females) with solid SPN who underwent surgical resection with definite postoperative pathological diagnosis from January 2012 to December 2014 in Shanghai Chest Hospital (group A)were retrospectively analyzed. The clinical data included age, gender, history of smoking, history of tumor; radiologic data included diameter in lung window, location, shape, clear border, lobulation, spiculation, vascular convergence, tumor cycle blood vessel, density, calcification, pleura indentation; laboratory examination included five serum tumor markers consisting of CA125, CEA, CYFRAL21-1, NSE, SCC. (18)F-Fluorodeoxyglucose examinations included (18)F-FDG PET-CT or SPECT. The independent predictors of malignancy were esti
doi_str_mv 10.3760/cma.j.issn.0376-2491.2016.17.011
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source MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Biomarkers, Tumor
CA-125 Antigen
Calcinosis
China
Female
Fluorodeoxyglucose F18
Humans
Lung Neoplasms
Male
Multivariate Analysis
Pleura
Probability
Retrospective Studies
ROC Curve
Smoking
Solitary Pulmonary Nodule
Thorax
title Establishment of a predicting model to evaluate the probability of malignancy or benign in patients with solid solitary pulmonary nodules
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