Morphology of Nasal Lesions in F344/N Rats Following Chronic Inhalation Exposure to Naphthalene Vapors

Naphthalene (CAS No. 91-20-3) administered by inhalation at concentrations of 10, 30, or 60 ppm for 6 hours per day, 5 days per week for 105 weeks caused nonneoplastic and neoplastic effects in nasal respiratory and olfactory regions of male and female F344/N rats. Non-neoplastic nasal effects were...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicologic pathology 2003-11, Vol.31 (6), p.655-664
Hauptverfasser:	Long, Philip H., Herbert, Ronald A., Peckham, John C., Grumbein, Sondra L., Shackelford, Cynthia C., Abdo, Kamal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - chemically induced Adenoma - pathology Administration, Inhalation Animals Biological and medical sciences Carcinogens - administration & dosage Carcinogens - toxicity Chemical and industrial products toxicology. Toxic occupational diseases Dose-Response Relationship, Drug Female Inhalation Exposure - adverse effects Male Medical sciences Naphthalenes - administration & dosage Naphthalenes - toxicity Nasal Mucosa - drug effects Nasal Mucosa - pathology Neuroblastoma - chemically induced Neuroblastoma - pathology Nose Neoplasms - chemically induced Nose Neoplasms - pathology Rats Rats, Inbred F344 Toxicology Various organic compounds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!