Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations

This study was undertaken to determine the effects of occupation, lifestyle and the genetic polymorphisms of cytochrome P450 1A1 (CYP1A1), cytochrome P450 2E1 (CYP2E1) and glutathione S-transferases μ1 (GSTM1) and Θ1 (GSTT1) on the concentrations of urinary 1-hydroxypyrene (1-OHP) and 2-naphthol amo...

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Veröffentlicht in:	Carcinogenesis (New York) 2001-05, Vol.22 (5), p.787-793
Hauptverfasser:	Nan, Hong-Mei, Kim, Heon, Lim, Hyun-Sul, Choi, Jung Keun, Kawamoto, Toshihiro, Kang, Jong-Won, Lee, Chul-Ho, Kim, Yong-Dae, Kwon, Eun Hye
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Hydroxypyrene 1-OHP 2-Naphthol Base Sequence Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases coke oven workers CYP CYP1A1 gene CYP2E1 gene Cytochrome P-450 CYP1A1 - genetics Cytochrome P-450 CYP2E1 - genetics cytochrome P450 cytochromes P-450 DNA Primers Female glutathione S-transferase Glutathione Transferase - genetics GST GSTM1 gene GSTT1 gene Humans Life Style lifestyle Male Medical sciences naphthalene Naphthols - urine Occupations PAH polycyclic aromatic hydrocarbon Polymorphism, Genetic pyrene Pyrenes - metabolism total suspended particulate Toxicology TSP Various organic compounds
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