Antibodies to human neutrophil antigen HNA-4b implicated in a case of neonatal alloimmune neutropenia

BACKGROUND Maternal alloantibodies directed against human neutrophil antigens (HNAs) can cause moderate‐severe neutropenia in the newborn in a condition known as neonatal alloimmune neutropenia (NAIN). Neonates with NAIN can present with sepsis or be asymptomatic. NAIN has previously been reported a...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2016-05, Vol.56 (5), p.1161-1165
Hauptverfasser:	Mraz, G.A., Crighton, G.L., Christie, D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody Specificity Female Granulocytes Granulocytes - immunology Humans Immunoglobulins Infant, Newborn Infant, Newborn, Diseases - immunology Isoantibodies - blood Isoantigens - immunology Mothers Neutropenia Neutropenia - immunology Neutrophils Neutrophils - immunology
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