Fine‐mapping of two differentiated thyroid carcinoma susceptibility loci at 9q22.33 and 14q13.3 detects novel candidate functional SNPs in Europeans from metropolitan France and Melanesians from New Caledonia

Incidence of differentiated thyroid carcinoma varies considerably between countries and ethnic groups, with particularly high incidence rates in Melanesians of New Caledonia. Differentiated thyroid cancer (DTC) has a familial relative risk higher than other cancers, highlighting the contribution of...

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Veröffentlicht in:	International journal of cancer 2016-08, Vol.139 (3), p.617-627
Hauptverfasser:	Tcheandjieu, Catherine, Lesueur, Fabienne, Sanchez, Marie, Baron‐Dubourdieu, Dominique, Guizard, Anne‐Valerie, Mulot, Claire, Laurent‐Puig, Pierre, Schvartz, Claire, Truong, Therese, Guenel, Pascal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Cancer cancer genetics Case-Control Studies case–control study Chromosome Mapping Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 9 Computational Biology - methods Female fine‐mapping study France Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Genotype Haplotypes Humans Linkage Disequilibrium Male Medical research Melanesia Middle Aged New Caledonia Odds Ratio Polymorphism Polymorphism, Single Nucleotide Population Surveillance Quantitative Trait Loci Risk Factors Thyroid cancer Thyroid Neoplasms - epidemiology Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology
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