Identification and Characterization of a Phosphoinositide Phosphate Kinase Homolog

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) plays a central role in regulating the actin cytoskeleton as a substrate for phosphoinositide 3-kinase and phospholipase C as well as by binding directly to proteins that control the processes of actin monomer sequestration, filament severing, cappin...

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Veröffentlicht in:The Journal of biological chemistry 2004-03, Vol.279 (12), p.11672-11679
Hauptverfasser: Chang, James D., Field, Seth J., Rameh, Lucia E., Carpenter, Christopher L., Cantley, Lewis C.
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Sprache:eng
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